Vitamin A Compound Might Aid in Colon Cancer Fight - Hallo friendsLET'S HEALTHY LIFE, In the article you read this time with the title Vitamin A Compound Might Aid in Colon Cancer Fight, We have prepared this article for you to read and retrieve information therein. Hopefully the contents of postings Article cough, Article diabetes, Article diseases, Article in general, Article Phytotherapy, Article skin diseases, We write this you can understand. Alright, good read.

Title : Vitamin A Compound Might Aid in Colon Cancer Fight
link : Vitamin A Compound Might Aid in Colon Cancer Fight

Vitamin A Compound Might Aid in Colon Cancer Fight

In continuation of my update on Retinoic acid

Retinoic acid, a compound derived in the body from vitamin A, might have a role in suppressing colon cancer, new animal research suggests.

"Retinoic acid has been known for years to be involved in suppressing inflammation in the intestine," said study senior author Dr. Edgar Engleman, professor of pathology and medicine at Stanford University School of Medicine in Palo Alto, Calif.

Meanwhile, the development of colon cancer has been linked to inflammation. For example, inflammatory bowel disease, such as ulcerative colitis, has been associated with colon cancer, he said in a university news release.

"We wanted to connect the dots and learn whether and how retinoic acid levels directly affect cancer development," Engleman added.

When the researchers looked at mice with colon cancer, they saw lower levels of retinoic acid in the intestines of the mice.

The researchers also found that boosting levels of retinoic acid in the intestines of mice with colon cancer slowed progression of the disease.

In humans, colon cancer patients who had high levels of a protein that degrades retinoic acid in their intestinal tissue tended to have worse outcomes than other patients, the study authors noted.

The findings suggest new ways to prevent or treat colon cancer. However, it's important to note that animal research doesn't always produce the same results in humans.

"The intestine is constantly bombarded by foreign organisms. As a result, its immune system is very complex," Engleman said.

"We found that bacteria, or molecules produced by bacteria, can cause a massive inflammatory reaction in the gut that directly affects retinoic acid metabolism," he said.

He said that retinoic acid levels are normally regulated very tightly.

"Now that we've shown a role for retinoic acid deficiency in colorectal cancer, we'd like to identify the specific microorganisms that initiate these changes in humans. Ultimately we hope to determine whether our findings could be useful for the prevention or treatment of colorectal cancer," he concluded.

The study was published online Aug. 30 in the journal Immunity.

Vitamin A Compound Might Aid in Colon Cancer Fight

Medicinal Chemistry

Thus Article Vitamin A Compound Might Aid in Colon Cancer Fight

That's an article Vitamin A Compound Might Aid in Colon Cancer Fight This time, hopefully can give benefits to all of you. well, see you in posting other articles.

You are now reading the article Vitamin A Compound Might Aid in Colon Cancer Fight with the link address https://letslifes.blogspot.com/2017/06/vitamin-compound-might-aid-in-colon.html

Tweet

Subscribe to receive free email updates: