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Title : And Now For Something Completely Different
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And Now For Something Completely Different

Wnt signaling may be involved in the variation of opossum color. From the abstract: “Previous morphological studies have found that skin pigmentation variation in the Virginia opossum (Didelphis virginiana) is associated with variation in precipitation and temperatures across its distribution range following Gloger's rule (lighter pigmentation in temperate environments). To investigate the molecular mechanism associated with skin pigmentation variation, we used RNA-Seq and quantified gene expression of wild opossums from tropical and temperate populations. Using differential expression analysis and a coexpression network approach, we found that expression variation in genes with melanocytic and immune functions are significantly associated with the degree of skin pigmentation variation and may be underlying this phenotypic difference. We also found evidence suggesting that the Wnt/β-catenin signaling pathway might be regulating the depigmentation observed in temperate populations.”

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