Parkinson's Disease: Mitochondria Parked at the ER Hit the Snooze Button

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Title : Parkinson's Disease: Mitochondria Parked at the ER Hit the Snooze Button
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Parkinson's Disease: Mitochondria Parked at the ER Hit the Snooze Button

A study evaluates the role of Parkinson’s disease genes in the sleep disturbances that accompany the disease.  Abstract:

Parkinson's disease patients report sleep disturbances well ahead of motor symptoms. In this issue of Neuron, Valadas et al. (2018) report that the disease genes pink1 and parkin exert novel, cell-type-specific effects to modulate ER-mitochondria contacts, neuropeptidergic transmission, and sleep patterns.



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